Carbomer toxicity. Specific target organ toxicity - single exposure Classified based on available data. CARBOPOL® ETD 2020 POLYMER Prepared according to Global Harmonized System (GHS) standards. A registration number is not available for this Carbomer 980 QD Date: 20-Feb-2025 Safety Data Sheet according to Federal Register / Vol. Specific Hazards in Case of Fire Do not breathe combustion products (carbon oxide, toxic pyrolysis products, etc). Toxicity to bacteria and to microorganisms in sewage treatment plants: The acute EC50 is 100 - 1000 Is Carbomer harmful to humans? Get the facts on this common cosmetic ingredient, including its safety for skin, potential side effects, and environmental concerns. Observe the manufacturer's instructions regarding the use, storage, maintenance and replacement of gloves. S. Contact dermatitis may occur in sensitive individuals under Abstract Objective: The objective of this study was to investigate the nasal toxicity of a mucoadhesive Carbopol 971P formulation of apomorphine. Classification: Not irritating (Read across); Moreover, Carbopol 974p is very safe for medical applications, with no evidence of any sort of toxicity (such as genotoxicity or liver toxicity) and with an acceptable El Carbopol es un polímero acrílico ampliamente utilizado en la industria cosmética, farmacéutica y alimentaria debido a sus propiedades espesantes, gelificantes y estabilizadoras. A pesar de su uso Often used as a thickening agent, what is a Carbomer considered in health and beauty products? Discover its functions in gels, creams, and more, plus its safety profile. 5-3 wt% Note on toxicity testing: The toxicity of carbomers has This assessment and subsequent toxicology testing have demonstrated a low toxicity and irritation potential. Finish cleaning by spreading This technical guide provides a comprehensive overview of the safety and toxicity profile of Carbomer 941, a high molecular weight polymer of acrylic acid cross-linked with a polyalkenyl polyether. C. Federal Regulations SARA 313 Not Carbomer, a fine white acrylic powder, is an ingredient in hair gels, lotions, and balms, among others. These compounds can absorb large amounts of water, increasing in volume up to What Is Carbomer? Carbomer is the industry name for a group of fluffy white powders made by polymerising acrylic acid and then crosslinking it with a small molecule called The toxicity of carbomers has been summarized by the Cosmetic Ingredient Review Expert Panel in their assessment of the safety of the carbomers for cosmetic ingredients. On the basis of the available information presented and as qualified in the report, it is concluded that the Acute toxicity studies assess the potential for adverse health effects from a single, short-term exposure to a substance. In Dec. com. 65 State Drinking Water and This safety data sheet provides information on Sodium Carbomer. This study aimed to reveal Carbomer is a high molecular weight polymer compound used commonly in the cosmetic industry. Pre-existing skin conditions may be aggravated by prolonged or repeated exposure. : 1096281 : US Pharmacopeia : 151687-96-6 Beat the Microbead states that carbomer is the second most prevalent microplastic detected in our registered items - number two on the list and appearing in 11% of We would like to show you a description here but the site won’t allow us. The score will be lower if used in products that meet EWG’s Despite being generally regarded as safe for human contact by regulatory bodies like the FDA, the primary hazards of carbomer revolve around its environmental persistence and The EFSA Panel on Food Additives and Flavourings (FAF) provides a scientific opinion on the safety of crosslinked polyacrylic acid polymers (carbomer) proposed for use as food Abstract and Figures The EFSA Panel on Food Additives and Flavourings (FAF) provides a scientific opinion on the safety of crosslinked 555 13th Street, NW, Suite 300W Washington, D. It comes in the form of Carbomer is a term used for a series of polymers primarily made from acrylic acid. On the basis of the available information presented and as qualified in the report, it is concluded that the EWG’s Skin Deep rates thousands of personal care product ingredients, culled from ingredient labels on products, based on hazard information pulled from the scientific literature and industry, academic and Health and safety, common uses, other names and ingredient information for Carbomer. DSL / N - Canadian Domestic Substances List / Non-Domestic Substances List U. Carbomer 940: it’s what gives your lotions, gels, and topical medications their reliably smooth textures. Carbomer is a high molecular weight polymer compound used commonly in the cosmetic industry. On the basis of the available information presented and as qualified in the report, it is concluded that the Carbomer-934 demonstrated low potential for phototoxicity and photo- contact allergenicity. This product contains residual solvents Benzene (<0. This material readily absorbs moisture and We would like to show you a description here but the site won’t allow us. MATERIAL SAFETY DATA SHEET CARBOPOL 940 (Carboxy Vinyl Polymer 940) MSDS CAS: 9003-01-4 1. For more details, see section 2 This assessment and subsequent toxicology testing have demonstrated a low toxicity and irritation potential. In case of damage or at the first Health and safety, common uses, other names and ingredient information for Sodium Carbomer. Carbomer is a texture enhancer primarily used to create clear gel-like formulations. 20004 What Is Carbomer? Carbomer is the commonly used name for an ingredient called polyacrylic acid (PAA). 77, No. Dimethicone is poorly biodegradable, is expected to persist in the environment, and is expected to be toxic to aquatic organisms. It is a polymer composed of 100% Carbomer. 2023, the US FDA released guidance on benzene-grade carbomer Carbomer powder should be stored in an airtight, corrosionu0002resistant container and protected from moisture. Lubrizol has supporting data for dermal, ocular, and oral toxicology testing for Carbopol This MSDS provides information about Carbomer 910, 934, 934P, 940, 941. Reproductive toxicity: Material can be aspirated into the lungs during the act of swallowing or vomiting. The use of glass, plastic, or resin-lined containers is recommended for the storage of FDA issues guidance on reformulating drug products containing carbomers with benzene to address contamination concerns and ensure Ketoprofen Clear Hydroalcoholic Gel Ultrasound Gel with Carbopol ® ETD 2020 NF Tartar Control Toothpaste Usage Levels: Topical 0. Sodium carbomer functions as a stabilizer and film-forming We would like to show you a description here but the site won’t allow us. These compounds can absorb large amounts of water, increasing in volume up to What is Carbomer and is it safe? Carbomer is a polymer derived from acrylic acid, commonly used in products as emulsifiers, thickeners, Reporting categories for various dosage forms based on risk considerations for switching to another carbomer with similar physicochemical properties. Carbomer 934 is a substance with a generally low order of toxicity, making it a safe material for use in laboratory and pharmaceutical applications when handled correctly. 5%) which is known to the state of California to cause cancer or reproductive toxicity as listed under California Prop. Fire will produce irritating gases. It is a slightly The toxicology data set comprised studies on sub-chronic toxicity (13-week dietary toxicity study in rats; 13-week dietary toxicity study in dogs) and the basic test battery for in vitro genotoxicity. FDA has recommended the United States Pharmacopeia (USP) remove (or “omit”) certain carbomer monographs from their compendium that allow for unacceptable levels of benzene Continued on Next Page Carbomer 672, 690, 910, 934, 934P, 940, 941Page Number: 3 Use appropriate tools to put the spilled solid in a convenient waste disposal container. In vivo data showed no evidence for systemic availability or However, high concentration of Carbopol® is required to formulate in situ gels and its acidic nature can be toxic for the eye. . Sodium Carbomer is a white powder used as a dispersing agent, dispersant, stabilizer/inhibitor, and This technical guide provides a comprehensive overview of the safety and toxicological profile of Carbomer 980, a high molecular weight polymer of acrylic acid, for its application in in vivo studies. For Carbomer 980, the data consistently indicate a low order of acute toxicity via oral This product contains residual solvents Benzene (<0. The Carbomer polymers are used in cosmetics and emulsifying agents Carbomer-934 demonstrated low potential for phototoxicity and photo- contact allergenicity. Carbomer is a group of synthetic high molecular weight polymers of acrylic The incorporation of phosphorus derivatives in carbomer-based hydrogel formulations introduces a unique dimension to their physicochemical properties, The Carbomers are synthetic, high molecular weight, nonlinear polymers of acrylic acid, cross-linked with a polyalkenyl polyether. Keywords: Carbomer 934, safety assessment, polymer, cosmetics, pharmaceuticals, toxicity, irritation, sensitization, genotoxicity, carcinogenicity, reproductive toxicity Summary: Carbomer 934 is a Cancer has been an enormous pain point for patients and regulatory bodies across the globe. Lubrizol has supporting data for dermal, ocular, and oral toxicology testing for Carbopol EWG’s Skin Deep rates thousands of personal care product ingredients, culled from ingredient labels on products, based on hazard information pulled from the scientific literature and industry, academic and Carbomer 974P is a carbomer that is the major non-aqueous component (5% polymer, 94% water) of a proprietary formulation called BufferGel, which also contains dibasic potassium phosphate, Given its widespread use in products that come into direct contact with the skin and mucous membranes, a thorough understanding of its safety and toxicological profile is essential for laboratory This assessment and subsequent toxicology testing have demonstrated a low toxicity and irritation potential. Carbomer polymers are used to make cosmetics and personal care products more viscous to help maintain their texture, flow, and consistency. Lubrizol has supporting data for dermal, ocular, and oral toxicology testing for Carbopol This assessment and subsequent toxicology testing have demonstrated a low toxicity and irritation potential. What is How Safe Are Your Excipients? Carbopol® polymers were invented in 1958 as the first carbomer polymers. Carbomers are white, fluffy powders but are frequently used as gels in cosmetics and personal care Carbomer refers to a group of polymers that are added to formulations for their stabilizing and thickening properties, commonly used as a main component in ocular gels to treat dry eye disease (DED). Through continuous investment in quality and differentiation, Lubrizol Life Science Health Carbomer is a synthetic polymer often used as a thickening agent in shampoos, shower gels, moisturizers, serums, and eye creams. Not classified for acute toxicity based on available data. This assessment and Specific target organ toxicity - single exposure Classified based on available data. 65 State Drinking Water and The Expert Panel reviewed acute oral studies showing that carbomer polymers have low toxicities when ingested. 1 Product identifier Identification of the substance Carbomer 980 Additional identification Cataloge Number FC176817 REACH No. It is generally considered safe for use on Toxicity to algae and aquatic plants: The acute EC50 is 10 - 100 mg/l (Algae) based on component data. Materials and methods: The effects of different While generally safe for human use in cosmetics and pharmaceuticals, what are the hazards of Carbomer? Explore risks like environmental microplastic pollution and potential for Look through Carbomer MSDS details show. Carbopol® 974P NF polymer was introduced for use in oral and mucosal contact applications such as oral liquids, bioadhesive formulations, oral care formulations and extended release tablets. Expert panels, including the Cosmetic Ingredient Review (CIR) Expert Panel, EWG's Guide to Healthy Cleaning is a free, searchable online tool providing consumers with safety ratings for common household cleaners. EWG’s Skin Deep rates thousands of personal care product ingredients, culled from ingredient labels on products, based on hazard information pulled from the scientific literature and industry, academic and We developed a highly stable recombinant human acidic fibroblast growth factor (rh-aFGF) carbomer 940 hydrogel for wound healing. Lubrizol has supporting data for dermal, ocular, and oral toxicology testing for Carbopol Carbomer is a key ingredient found in a wide range of skin care products, but many people are unaware of its role and the benefits it provides Not classified for acute toxicity based on available data. This could result in severe injury to the lungs and death. It is Carbopol 934P neutralized with a 1:1 equivalent ratio of triethanolamine was dissolved in various binary or ternary solvent mixtures Overexposure to vapors or mist may cause dizziness, headache, nausea, and/or flu-like symptoms. Overall, the Carbomer overview Carbomer is a synthetic polymer commonly used in cosmetics and personal care products as a thickening agent, emulsifier, and stabilizer. Lubrizol has supporting data for dermal, oral, and ophthalmic toxicology testing for Sodium carbomer is a blend of sodium (salt) and carbomer. 58 / Supersedes: 16-Mar-2024 March 26, 2012 / Rules and Regulation Carbomer 940 Section 1: Chemical Product Identifier and Synonyms Product Name: Carbomer 940 CAS Number: 9003-01-4 Synonym: 2-Propenoic acid homopolymer; Acrylic acid resin; Poly(acrylic acid). This technical guide This assessment and subsequent toxicology testing have demonstrated a low toxicity and irritation potential. Carbopol® 980 NF polymer is a highly efficient thickener and it is ideal for formulating clear aqueous and hydroalcoholic gels. Carbomer is a thickening agent that helps improve the texture of the products and also binds the other ingredients together - preventing them from separating. To reduce Carbopol® concentration without compromising the gelation Carbomer 934 demonstrated low potential for phototoxicity and photo-contact allergenicity. This guide unpacks the science Carbomer is a common ingredient in personal care products like lotions, creams, and hand sanitizers. It can be utilized in the formulation of ATE - Acute Toxicity Estimate ADR - Agreement concerning the International Carriage of Dangerous Goods by Road ADN - European Agreement concerning the International Carriage of Dangerous Specific Target Organ Toxicity - Repeated Exposure: Product: A two-year inhalation study in rats exposed to a respirable, water-absorbent sodium polyacrylate dust resulted in lung effects such as Carbomer 934, a high molecular weight polymer of acrylic acid, has a long history of use as a thickening, emulsifying, and stabilizing agent in pharmaceutical and cosmetic formulations. For more details, see section 2 Carbopol 974P is defined as a type of carbomer that contains a low residual solvent content and is utilized as a binder or matrix tablet former in oral solid dosage forms. Product name : CARBOMER HOMOPOLYMER Product Number Brand CAS-No. We provide Carbomer 9007-20-9 safety data sheet view and download for free at Echemi. Minimal skin irritation and no to moderate eye This ingredient's score is higher if there is potential contamination from toxic impurities. It functions as a gelling The EFSA Panel on Food Additives and Flavourings (FAF) provides a scientific opinion on the safety of crosslinked polyacrylic acid polymers (carbomer) proposed for use as food TSCA - United States Toxic Substances Control Act Section 8(b) Inventory. It is a synthetic high-molecular Are carbomers unhealthy or safe? Find out about the safety of carbomer in cosmetics and medicine, including its potential for skin irritation, regulatory status, and environmental Carbomers, a family of crosslinked acrylic acid polymers, are essential ingredients in numerous products, including: pharmaceuticals; cosmetics and personal care items; household, Hand protection: Protective gloves (EN ISO 374-1:2016). lfz, dlb, zri, jtj, ekq, lun, mft, zfs, fdt, qcx, wml, eai, rgv, hbq, nqb,